Article
The motor phenotype of Parkinson's disease in relation to age at onset.
Movement disorders : official journal of the Movement Disorder Society - 15 Feb 2011
Wickremaratchi Mirdhu M, Knipe M Duleeka W, Sastry B S Dwarakanath, Morgan Elizabeth, Jones Anne, Salmon Rachel, Weiser Richard, Moran Maralyn, Davies Debbie, Ebenezer Louise, Raha Sandip, Robertson Neil P, Butler Christopher C, Ben-Shlomo Yoav, Morris Huw R
Abstract excerpt
BACKGROUND: Parkinson's disease (PD) is heterogeneous and age at onset may define variation in clinical phenotype. Most previous studies have used various age cut-offs and have been based on clinical case series. METHODS: We have studied the association between clinical features and age of onset in 358 community-based and regional patients with PD. RESULTS: Tremor at presentation is twice as common in those with...
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