Article
Morphological reversion of sis-transformed NIH3T3 cells by trichostatin A.
Cancer research - 1 Jan 1992
Sugita K, Koizumi K, Yoshida H
Abstract excerpt
Trichostatin A (TSA) induced the normal and flat phenotype of sis-transformed NIH3T3 cells at quite a low concentration of 1 ng/ml. Although morphological changes were found in other oncogene-transformed cells, they were not the same as those seen for the sis-transformed cells. Almost complete re...
Topics
- 3T3 Cells
- Animals
- Cell Line, Transformed
- Cycloheximide
- Hydroxamic Acids
- Mice
- Oncogenes
- Phenotype
- RNA, Messenger
- Transfection