Article
Modulation of ras transformation affecting chromatin supraorganization as assessed by image analysis.
Experimental cell research - 1 Oct 1995
Mello M L, Contente S, Vidal B C, Planding W, Schenck U
Abstract excerpt
Changes in chromatin supraorganization defined in terms of patterns of chromatin texture were studied by video image analysis in Feulgen-stained revertants of LTR-ras-transformed NIH 3T3 cells and in cell lines obtained by transfection of these revertants with sense and antisense constructs of the lysyl oxidase gene (also named Lox or "ras recision gene"). The objective was to determine whether changes in...
Topics
- 3T3 Cells
- Animals
- Cell Line
- Cell Nucleus
- Cell Transformation, Neoplastic
- Chromatin
- Coloring Agents
- Genes, ras
- Humans
- Interferon Type I
- Mice
- Phenotype
