Article
Genetics of recurrent early-onset major depression (GenRED): significant linkage on chromosome 15q25-q26 after fine mapping with single nucleotide polymorphism markers.
The American journal of psychiatry - 1 Feb 2007
Levinson Douglas F, Evgrafov Oleg V, Knowles James A, Potash James B, Weissman Myrna M, Scheftner William A, Depaulo J Raymond, Crowe Raymond R, Murphy-Eberenz Kathleen, Marta Diana H, McInnis Melvin G, Adams Philip, Gladis Madeline, Miller Erin B, Thomas Jo, Holmans Peter
Abstract excerpt
OBJECTIVE: The authors studied a dense map of single nucleotide polymorphism (SNP) DNA markers on chromosome 15q25-q26 to maximize the informativeness of genetic linkage analyses in a region where they previously reported suggestive evidence for linkage of recurrent early-onset major depressive disorder. METHOD: In 631 European-ancestry families with multiple cases of recurrent early-onset major depressive...
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