A genome-wide significant linkage for severe depression on chromosome 3: the depression network study.

doi:10.1176/appi.ajp.2011.10091342

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Article

A genome-wide significant linkage for severe depression on chromosome 3: the depression network study.

The American journal of psychiatry - 1 Aug 2011

Breen Gerome, Webb Bradley Todd, Butler Amy W, van den Oord Edwin J C G, Tozzi Federica, Craddock Nick, Gill Mike, Korszun Ania, Maier Wolfgang, Middleton Lefkos, Mors Ole, Owen Michael J, Cohen-Woods Sarah, Perry Julia, Galwey Nicholas W, Upmanyu Ruchi, Craig Ian, Lewis Cathryn M, Ng Mandy, Brewster Shyama, Preisig Martin, Rietschel Marcella, Jones Lisa, Knight Jo, Rice John, Muglia Pierandrea, Farmer Anne E, McGuffin Peter

Abstract excerpt

OBJECTIVE: The purpose of this study was to find loci for major depression via linkage analysis of a large sibling pair sample. METHOD: The authors conducted a genome-wide linkage analysis of 839 families consisting of 971 affected sibling pairs with severe recurrent major depression, comprising waves I and II of the Depression Network Study cohort. In addition to examining affected status, linkage analyses in...

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Identifiers

PMID: 21572164
DOI: 10.1176/appi.ajp.2011.10091342

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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