Article
Genetics of recurrent early-onset major depression (GenRED): final genome scan report.
The American journal of psychiatry - 1 Feb 2007
Holmans Peter, Weissman Myrna M, Zubenko George S, Scheftner William A, Crowe Raymond R, Depaulo J Raymond, Knowles James A, Zubenko Wendy N, Murphy-Eberenz Kathleen, Marta Diana H, Boutelle Sandra, McInnis Melvin G, Adams Philip, Gladis Madeline, Steele Jo, Miller Erin B, Potash James B, Mackinnon Dean F, Levinson Douglas F
Abstract excerpt
OBJECTIVE: The authors carried out a genomewide linkage scan to identify chromosomal regions likely to contain genes that contribute to susceptibility to recurrent early-onset major depressive disorder, the form of the disorder with the greatest reported risk to relatives of index cases. METHOD: Microsatellite DNA markers were studied in 656 families with two or more such cases (onset before age 31 in probands...
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