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Article

Linkage disequilibrium mapping of a chromosome 15q25-26 major depression linkage region and sequencing of NTRK3.

Biological psychiatry - 15 Jun 2008

Verma Ranjana, Holmans Peter, Knowles James A, Grover Deepak, Evgrafov Oleg V, Crowe Raymond R, Scheftner William A, Weissman Myrna M, DePaulo J Raymond, Potash James B, Levinson Douglas F

Abstract excerpt

BACKGROUND: We reported genome-wide significant linkage on chromosome 15q25.3-26.2 to recurrent early-onset major depressive disorder (MDD-RE). Here we present initial linkage-disequilibrium (LD) fine mapping of this signal and sequence analysis of NTRK3 (neurotrophic receptor kinase-3), a biolog...

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Topics

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Share to Chromosomes, Human, Pair 15
Share to Depressive Disorder, Major

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Carrier Screening

Share to Introns

Share to Linkage Disequilibrium

Share to Mutation, Missense

Share to Receptor, trkC

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Source

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Identifiers

PMID: 18367154
DOI: 10.1016/j.biopsych.2008.02.005
PMCID: PMC2435230

Genes

NTRK3
MCTP2
RGMA
RHCG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18367154-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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