Genome-wide linkage analyses of extended Utah pedigrees identifies loci that influence recurrent, early-onset major depression and anxiety disorders.

doi:10.1002/ajmg.b.30177

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Article

Genome-wide linkage analyses of extended Utah pedigrees identifies loci that influence recurrent, early-onset major depression and anxiety disorders.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 May 2005

Camp Nicola J, Lowry Michael R, Richards R Lynn, Plenk Agnes M, Carter Catherine, Hensel Charles H, Abkevich Victor, Skolnick Mark H, Shattuck Donna, Rowe Kerry G, Hughes Dana C, Cannon-Albright Lisa A

Abstract excerpt

Major depressive disorder (MDD) is a common, clinically heterogeneous disorder often found comorbid with other disorders. We studied recurrent, early-onset MDD (MDD-RE) and anxiety disorders in combination to define powerful phenotypes for genetic study. We used 87 large, extended Utah pedigrees to investigate linkage to 3 phenotypes: "MDD-RE;" "MDD-RE or anxiety;" and "MDD-RE and anxiety;" where in the latter...

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PMID: 15806581
DOI: 10.1002/ajmg.b.30177

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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