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Article

Estimates of array and pool-construction variance for planning efficient DNA-pooling genome wide association studies.

BMC medical genomics - 28 Nov 2011

Earp Madalene A, Rahmani Maziar, Chew Kevin, Brooks-Wilson Angela

Abstract excerpt

BACKGROUND: Until recently, genome-wide association studies (GWAS) have been restricted to research groups with the budget necessary to genotype hundreds, if not thousands, of samples. Replacing individual genotyping with genotyping of DNA pools in Phase I of a GWAS has proven successful, and dramatically altered the financial feasibility of this approach. When conducting a pool-based GWAS, how well SNP allele...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22122996
DOI: 10.1186/1755-8794-4-81
PMCID: PMC3247851

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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