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Article

HLA class I epitopes accounted for by single residues.

Clinical transplants - 1 Jan 1991

Park M S, Clark B D, Maruya E, Terasaki P I

Abstract excerpt

We examined the serological reaction of 50,000 HLA antisera for correlations with amino acid substitutions at 16 variable residues on the A locus and 8 variable residues on the B locus. We identified antisera that produced mutually exclusive allelic reactions corresponding to amino acid variants at the various residues. We assumed that by this procedure, epitopes that were determined by a single amino acid...

Topics

Alleles
Amino Acid Sequence
Chromosome Mapping
Epitopes
Gene Frequency
Histocompatibility Antigens Class I
Histocompatibility Testing
Humans

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 1726460

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1726460-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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