Article
HLA class I epitopes accounted for by single residues.
Clinical transplants - 1 Jan 1991
Park M S, Clark B D, Maruya E, Terasaki P I
Abstract excerpt
We examined the serological reaction of 50,000 HLA antisera for correlations with amino acid substitutions at 16 variable residues on the A locus and 8 variable residues on the B locus. We identified antisera that produced mutually exclusive allelic reactions corresponding to amino acid variants at the various residues. We assumed that by this procedure, epitopes that were determined by a single amino acid...
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