Article
Conserved and variable structures in HLA class I molecules: a review.
Tissue antigens - 1 Mar 1990
Colombani J
Abstract excerpt
Amino acid sequences and structural data on HLA class I molecules are now available, making possible a comparison of the serological and structural definitions of allelic series. 1) A hierarchy of differences between molecules is observed. Certain molecules show a low level of differences (1.2% of amino acids) and represent variants of original molecules. Other molecules are recombinants derived from two parent...
Topics
- Antibodies, Monoclonal
- Cross Reactions
- Epitopes
- Genetic Variation
- HLA Antigens
- Histocompatibility Antigens Class I
- Humans
- Molecular Structure
- Polymorphism, Genetic
- T-Lymphocytes
