Article
Correlating sequence variation with HLA-A allelic families: implications for T cell receptor binding specificities.
Immunology and cell biology - 1 Apr 1998
Jakobsen I B, Gao X, Easteal S, Chelvanayagam G
Abstract excerpt
Six families of HLA-A alleles have been previously proposed on the basis of nucleotide sequence and phylogenetic analysis. Here, sequence polymorphism has been examined at both the protein and DNA levels in a family specific manner and new minimal signatures for each of the families have been delineated. The DNA and protein sites that constitute these signatures are distributed throughout the length of the...
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