Article
Identification of T-cell epitopes using allele-specific ligand motifs.
Behring Institute Mitteilungen - 1 Dec 1994
Stevanović S, Rammensee H G
Abstract excerpt
In order to facilitate the identification of T-cell epitopes as useful components of synthetic vaccines, we investigated the role of MHC molecules as the restriction element for the recognition of epitopes by the alpha beta receptor of T cells. MHC molecules are able to present thousands of different peptides to T cells, with all the peptides presented by one distinct type of MHC sharing common structural...
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