Article
Epitopes and motifs of the HLA-B*14 allele family products and related HLA-B14 cross-reactive specificities.
International journal of immunogenetics - 1 Oct 2017
Street J, Darke C
Abstract excerpt
The split specificities of HLA-B14 (B64, B65) are assigned to the B*14:01 (B64) and B*14:02 (B65) products only. Of the further 50 B*14 expressed products, only B*14:03 and B*14:06 are officially designated as HLA-B14. The B*14:08 product differs from B64 by a single amino acid substitution of W97R, while the B*14:53 specificity (which is a "short" B14 and neither B64 nor B65) differs from B64 by three residues...
Topics
- Alleles
- Amino Acid Motifs
- Amino Acid Substitution
- Antibodies, Monoclonal
- Antibody Specificity
- Cross Reactions
- Epitopes
- HLA-B14 Antigen
- Humans
- Isoantibodies
