Article
A new strategy for systematically classifying HLA alleles into serological specificities.
HLA - 1 Sept 2022
Osoegawa Kazutoyo, Marsh Steven G E, Holdsworth Rhonda, Heidt Sebastiaan, Fischer Gottfried, Murphey Cathi, Maiers Martin, Fernández Viňa Marcelo A
Abstract excerpt
HLA serological specificities were defined by the reactivity of HLA molecules with sets of sera and monoclonal antibodies. Many recently identified alleles defined by molecular typing lack their serotype assignment. We surveyed the literature describing the correlation of the reactivity of serologic reagents with AA residues. 20 - 25 AA residues determining epitopes (DEP) that correlated with 82 WHO serologic...
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