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Article

Angiotensin-converting enzyme I/D polymorphism and macrovascular disease in systemic sclerosis.

Rheumatology (Oxford, England) - 1 May 2007

Bartoli F, Angotti C, Fatini C, Conforti M L, Guiducci S, Blagojevic J, Melchiorre D, Fiori G, Generini S, Damjanov N, Rednic S, Pignone A, Castellani S, Abbate R, Matucci Cerinic M

Abstract excerpt

OBJECTIVE: Systemic sclerosis (SSc) is characterized by microvascular and macrovascular alterations. The D allele of the ACE I/D polymorphism is known to be associated with an increased incidence of atherosclerosis and has been recently proposed as associated with increased risk of SSc. This study evaluates the relationship between intima-media thickness (IMT), ankle-brachial pressure measurements (ABPI) and ACE...

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Source

Identifiers

PMID: 17264090
DOI: 10.1093/rheumatology/kel433

Genes

ACE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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