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Article

Independent association of anti–β<sub>2</sub>‐glycoprotein I antibodies with macrovascular disease and mortality in scleroderma patients

30 Jul 2009

Abstract excerpt

OBJECTIVE: Systemic sclerosis (SSc; scleroderma) is characterized by a unique widespread vascular involvement that can lead to severe digital ischemia, pulmonary arterial hypertension (PAH), or other organ dysfunction. Microthrombotic events and procoagulation factors such as anti-beta2-glycoprotein I (anti-beta2GPI) or anticardiolipin antibodies (aCL) may be implicated in the development of these manifestations....

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PMID: 19644882
DOI: 10.1002/art.24684

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