Article
Etrurians vs Greeks: May ACE I/D polymorphism still be considered as a marker of susceptibility to SSc?
Clinical and experimental rheumatology - 1 Jan 2000
Guiducci S, Fatini C, Georgountzos A, Sticchi E, Cinelli M, Kaloudi O, Rogai V, Melchiorre D, Pignone A, Vlachoyannopoulos P, Abbate R, Matucci Cerinic M
Abstract excerpt
OBJECTIVE: SSc is characterized by immune dysfunction and microvascular involvement. A different genetic background may determine a different polymorphic allele frequency between different populations, and data from literature reported conflicting results about the role of genetic components in predisposing to the disease. We carried out this study in order to compare the ACE I/D polymorphism genotype...
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