Article
Angiotensin-converting enzyme insertion/deletion gene polymorphism is associated with dermatomyositis.
Journal of the renin-angiotensin-aldosterone system : JRAAS - 1 Sept 2015
Shinjo Samuel K, Uno Miyuki, Oba-Shinjo Sueli M, Marie Suely K N
Abstract excerpt
BACKGROUND AND OBJECTIVE: The cornerstone of dermatomyositis (DM) pathogenesis involves vascular disturbance that leads to hypoxia, capillary necrosis and muscle perifascicular atrophy. Hence, the hypothesis is that the angiotensin-converting enzyme (ACE) insertion/deletion (I/D) gene polymorphism could be associated with susceptibility to DM. METHOD: A single centre, case control study that genotyped ACE gene in...
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