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Article

Angiotensin-converting enzyme gene does not contribute to genetic susceptibility to systemic sclerosis in European Caucasians.

The Journal of rheumatology - 1 Feb 2009

Wipff Julien, Gallier Guillaume, Dieude Philippe, Avouac Jerome, Tiev Kiet, Hachulla Eric, Granel Brigitte, Diot Elisabeth, Sibilia Jean, Mouthon Luc, Meyer Olivier, Kahan Andre, Varret Mathilde, Boileau Catherine, Allanore Yannick

Abstract excerpt

OBJECTIVE: To determine whether angiotensin-converting enzyme (ACE) polymorphisms including I/D and 2 single-nucleotide polymorphisms (SNP) affect susceptibility to systemic sclerosis (SSc) in a large French Caucasian population. METHODS: A case-control study was performed in 494 patients with SSc and 280 healthy controls for I/D polymorphism. Two supplementary exonic SNP of ACE gene (rs4309, rs4362) were...

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Identifiers

PMID: 19132786
DOI: 10.3899/jrheum.080622

Genes

ACE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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