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Differential Changes inPlasmodium falciparum varTranscription during Adaptation to Culture

2 Feb 2007

Abstract excerpt

Plasmodium falciparum erythrocyte membrane protein 1, which is encoded by the var multigene family, is expressed on the surface of P. falciparum-infected erythrocytes and has been implicated in many of the complications associated with falciparum malaria. Transcriptional switching of var is commonly investigated using in vitro cultured parasites, because parasite material from patients is limited. We investigated...

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PMID: 17262719
DOI: 10.1086/511436

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