Article
Dominant-interfering C/EBPalpha stimulates primitive erythropoiesis in zebrafish.
Experimental hematology - 1 Feb 2007
Liu Ting Xi, Rhodes Jennifer, Deng Min, Hsu Karl, Radomska Hanna S, Kanki John P, Tenen Daniel G, Look A Thomas
Abstract excerpt
OBJECTIVE: We investigated the role of CCAAT enhancer-binding protein-alpha (C/EBPalpha) during zebrafish embryonic blood development. METHODS: Whole-mount mRNA in situ hybridization was performed to determine the spatio-temporal expression pattern of zebrafish cebpa in developing hematopoietic progenitors. A deletion mutation of cebpa (zD420), which mimics the human dominant-negative mutations of C/EBPalpha, was...
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