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Article

Mutations in PDLIM3 and MYOZ1 encoding myocyte Z line proteins are infrequently found in idiopathic dilated cardiomyopathy.

Molecular genetics and metabolism - 1 Apr 2007

Arola Anita M, Sanchez Ximena, Murphy Ross T, Hasle Aster, Li Hua, Elliott Perry M, McKenna William J, Towbin Jeffrey A, Bowles Neil E

Abstract excerpt

Dilated cardiomyopathy (DCM), characterized by ventricular dilation and decreased systolic function, is estimated to be of genetic origin in up to 50% of cases. In the present study, we investigated the role of two genes, encoding the Z line proteins PDZ and LIM domain protein 3 (PDLIM3) and myozenin-1 (MYOZ1), in the etiology of DCM. The coding regions of PDLIM3 and MYOZ1 were first amplified from the genomic...

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Source

Identifiers

PMID: 17254821
DOI: 10.1016/j.ymgme.2006.12.008

Genes

PDLIM3
MYOZ1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Mutations in PDLIM3 and MYOZ1 encoding myocyte Z line proteins are infrequently found in idiopathic dilated cardiomyopathy.PMID 17254821Read ↗

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