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Article

Impaired binding of ZASP/Cypher with phosphoglucomutase 1 is associated with dilated cardiomyopathy.

Cardiovascular research - 1 Jul 2009

Arimura Takuro, Inagaki Natsuko, Hayashi Takeharu, Shichi Daisuke, Sato Akinori, Hinohara Kunihiko, Vatta Matteo, Towbin Jeffrey A, Chikamori Taishiro, Yamashina Akira, Kimura Akinori

Abstract excerpt

AIMS: Z-band alternatively spliced PDZ-motif protein (ZASP)/Cypher is a Z-disc component of which several dilated cardiomyopathy (DCM)-associated mutations have been reported. Most of the mutations were found in exons 4 and 10 of ZASP/Cypher gene LDB3 and both exons were expressed preferentially in the heart. The aim of this study was to investigate the functional alteration of ZASP/Cypher caused by the...

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Topics

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Share to Adaptor Proteins, Signal Transducing
Share to Cardiomyopathy, Dilated

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chlorocebus aethiops

Share to COS Cells

Share to LIM Domain Proteins

Share to Myocytes, Cardiac

Share to Phosphoglucomutase

Share to Rats, Sprague-Dawley

Source

Identifiers

PMID: 19377068
DOI: 10.1093/cvr/cvp119

Genes

PGM1
LDB3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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