Article
Mutations in the Z-band protein myopalladin gene and idiopathic dilated cardiomyopathy.
Cardiovascular research - 1 Jan 2008
Duboscq-Bidot Laëtitia, Xu Peng, Charron Philippe, Neyroud Nathalie, Dilanian Gilles, Millaire Alain, Bors Valéria, Komajda Michel, Villard Eric
Abstract excerpt
AIMS: Idiopathic dilated cardiomyopathy (DCM) is a cardiac disorder characterized by left ventricular dilatation and impaired systolic contraction. It is a major cause of heart failure and heart transplantation. DCM is of genetic origin in approximately 30% of cases and genetically heterogeneous with the identification of numerous disease genes. However, many new disease genes remain to be discovered. Focusing on...
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