Mutations in Cypher/ZASP in patients with dilated cardiomyopathy and left ventricular non-compaction.

doi:10.1016/j.jacc.2003.10.021

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Article

Mutations in Cypher/ZASP in patients with dilated cardiomyopathy and left ventricular non-compaction.

Journal of the American College of Cardiology - 3 Dec 2003

Vatta Matteo, Mohapatra Bhagyalaxmi, Jimenez Shinawe, Sanchez Ximena, Faulkner Georgine, Perles Zeev, Sinagra Gianfranco, Lin Jiuann-Huey, Vu Thuy M, Zhou Qiang, Bowles Karla R, Di Lenarda Andrea, Schimmenti Lisa, Fox Michelle, Chrisco Michelle A, Murphy Ross T, McKenna William, Elliott Perry, Bowles Neil E, Chen Ju, Valle Giorgio, Towbin Jeffrey A

Abstract excerpt

OBJECTIVES: We evaluated the role of Cypher/ZASP in the pathogenesis of dilated cardiomyopathy (DCM) with or without isolated non-compaction of the left ventricular myocardium (INLVM). BACKGROUND: Dilated cardiomyopathy, characterized by left ventricular dilation and systolic dysfunction with signs of heart failure, is genetically transmitted in 30% to 40% of cases. Genetic heterogeneity has been identified with...

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PMID: 14662268
DOI: 10.1016/j.jacc.2003.10.021

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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