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Article

Serine phosphorylation by casein kinase II controls endocytic L1 trafficking and axon growth.

Journal of neuroscience research - 1 Mar 2007

Nakata Asuka, Kamiguchi Hiroyuki

Abstract excerpt

The cell adhesion molecule L1 plays crucial roles in axon tract development. In vitro, L1 presented as a culture substrate stimulates axon elongation by binding to L1 expressed on the growth cone. In migrating growth cones, L1 is endocytosed via the AP-2/clathrin-mediated pathway at the central domain, followed by anterograde vesicular transport and recycling to the plasma membrane of the leading front. It has...

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PMID: 17253643
DOI: 10.1002/jnr.21185

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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