Article
The kinesin-3 family motor KLP-4 regulates anterograde trafficking of GLR-1 glutamate receptors in the ventral nerve cord of Caenorhabditis elegans.
Molecular biology of the cell - 1 Sept 2012
Monteiro Michael I, Ahlawat Shikha, Kowalski Jennifer R, Malkin Emily, Koushika Sandhya P, Juo Peter
Abstract excerpt
The transport of glutamate receptors from the cell body to synapses is essential during neuronal development and may contribute to the regulation of synaptic strength in the mature nervous system. We previously showed that cyclin-dependent kinase-5 (CDK-5) positively regulates the abundance of GLR-1 glutamate receptors at synapses in the ventral nerve cord (VNC) of Caenorhabditis elegans. Here we identify a...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
