Article
Mutational analysis of the L1 neuronal cell adhesion molecule identifies membrane-proximal amino acids of the cytoplasmic domain that are required for cytoskeletal anchorage.
Molecular and cellular neurosciences - 1 Jan 1997
Dahlin-Huppe K, Berglund E O, Ranscht B, Stallcup W B
Abstract excerpt
The preferential localization of the L1 cell adhesion molecule in the axons and growth cones of differentiating neurons suggests the existence of a mechanism for targeting or anchoring the molecule to these locations. We have used B28 glioma cells, which have an extremely flattened morphology, as a model system to study the organization of L1 on the cell structure. Transfection of L1 cDNA into B28 cells results...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.