A second major histocompatibility complex susceptibility locus for multiple sclerosis.

doi:10.1002/ana.21063

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Article

A second major histocompatibility complex susceptibility locus for multiple sclerosis.

Annals of neurology - 1 Mar 2007

Yeo Tai Wai, De Jager Philip L, Gregory Simon G, Barcellos Lisa F, Walton Amie, Goris An, Fenoglio Chiara, Ban Maria, Taylor Craig J, Goodman Reyna S, Walsh Emily, Wolfish Cara S, Horton Roger, Traherne James, Beck Stephan, Trowsdale John, Caillier Stacy J, Ivinson Adrian J, Green Todd, Pobywajlo Susan, Lander Eric S, Pericak-Vance Margaret A, Haines Jonathan L, Daly Mark J, Oksenberg Jorge R, Hauser Stephen L, Compston Alastair, Hafler David A, Rioux John D, Sawcer Stephen

Abstract excerpt

OBJECTIVE: Variation in the major histocompatibility complex (MHC) on chromosome 6p21 is known to influence susceptibility to multiple sclerosis with the strongest effect originating from the HLA-DRB1 gene in the class II region. The possibility that other genes in the MHC independently influence...

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Identifiers

PMID: 17252545
DOI: 10.1002/ana.21063
PMCID: PMC2737610

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17252545-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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