Article
SNP mapping and candidate gene sequencing in the class I region of the HLA complex: searching for multiple sclerosis susceptibility genes in Tasmanians.
Tissue antigens - 1 Jan 2008
Burfoot R K, Jensen C J, Field J, Stankovich J, Varney M D, Johnson L J, Butzkueven H, Booth D, Bahlo M, Tait B D, Taylor B V, Speed T P, Heard R, Stewart G J, Foote S J, Kilpatrick T J, Rubio J P
Abstract excerpt
This study is an extension to previously published work that has linked variation in the human leukocyte antigen (HLA) class I region with susceptibility to multiple sclerosis (MS) in Australians from the Island State of Tasmania. Single nucleotide polymorphism (SNP) mapping was performed on an 865-kb candidate region (D6S1683-D6S265) in 166 Tasmanian MS families, and seven candidate genes [ubiquitin D (UBD),...
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