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Article

Variation, "evolution", immortality and genetic instabilities in tumour cells.

Cancer letters - 18 Aug 2007

Bignold L P

Abstract excerpt

The pathological characteristics of tumour cells often include variation of their histopathological features (i.e. "degrees of de-differentiation") between cases of the same tumour type and between different foci within individual tumours. Usually, only a few cell lines from tumours are immortal. Currently, somatic mutation, replicative infidelity of DNA and aneuploidy are suggested as alternative mechanisms of...

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Identifiers

PMID: 17250959
DOI: 10.1016/j.canlet.2006.12.007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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