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Article

Effect of DAB(389)IL-2 immunotoxin on the course of experimental autoimmune encephalomyelitis in Lewis rats.

Journal of the neurological sciences - 15 Dec 2007

Phillips S Michael, Bhopale Mahendra K, Constantinescu Cris S, Ciric Bogoljub, Hilliard Brendan, Ventura Elvira, Lavi Ehud, Rostami Abdolmohamad

Abstract excerpt

Activated T cells express the high affinity interleukin 2 receptor (IL-2R also CD25) that binds interleukin 2 (IL-2) and transduces signals important for the proliferation and survival of these cells. We investigated the effect of the genetically engineered immunotoxin DAB(389)IL-2 on experimental autoimmune encephalomyelitis (EAE), an autoimmune disease of the central nervous system (CNS) mediated by activated...

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PMID: 17603081
DOI: 10.1016/j.jns.2007.05.032

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MBP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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