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Article

High IFN-gamma production by CD8+ T cells and early sensitization among infants at high risk of atopy.

The Journal of allergy and clinical immunology - 1 Apr 2004

Rowe Julie, Heaton Tricia, Kusel Merci, Suriyaarachchi Devinda, Serralha Michael, Holt Barbara J, de Klerk Nick, Sly Peter D, Holt Patrick G

Abstract excerpt

BACKGROUND: High genetic risk (HR) of atopy among unstratified populations of infants is associated with attenuated IFN-gamma responses. However, the role of IFN-gamma in progression from HR status to active disease is less clear. OBJECTIVE: To identify immune function markers in neonates with HR that are associated with positive atopic outcomes at 2 years. METHODS: Cord blood mononuclear cells (CBMCs) were...

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Identifiers

PMID: 15100678
DOI: 10.1016/j.jaci.2003.12.585

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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