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Article

Divergent response profile in activated cord blood T cells from first-born child implies birth-order-associated in utero immune programming.

Allergy - 1 Mar 2016

Kragh M, Larsen J M, Thysen A H, Rasmussen M A, Wolsk H M, Bisgaard H, Brix S

Abstract excerpt

BACKGROUND: First-born children are at higher risk of developing a range of immune-mediated diseases. The underlying mechanism of 'birth-order effects' on disease risk is largely unknown, but in utero programming of the child's immune system may play a role. OBJECTIVE: We studied the association between birth order and the functional response of stimulated cord blood T cells. METHOD: Purified cord blood T cells...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26505887
DOI: 10.1111/all.12799

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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