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Article

High IL-13 production by human neonatal T cells: neonate immune system regulator?

1 Nov 2001

Abstract excerpt

Neonates are highly susceptible to diseases and display biased type 2 immune responses, although no skewing to type 2 cytokines has been reported. In view of the emerging importance of IL-13 in type 2 inflammatory responses and clinical allergy, we analyzed IL-13 production by neonatal T cells. We found that, mainly CD8 T cells produced high levels of IL-13, while producing low levels of IL-4, IL-10 and...

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PMID: 11745358
DOI: 10.1002/1521-4141(200111)31:11<3394::aid-immu3394>3.0.co;2-b

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