Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Functional polymorphism of the Anpep gene increases promoter activity in the Dahl salt-resistant rat.

Hypertension (Dallas, Tex. : 1979) - 1 Mar 2007

Kotlo Kumar, Hughes Douglas E, Herrera Victoria L M, Ruiz-Opazo Nelson, Costa Robert H, Robey R Brooks, Danziger Robert S

Abstract excerpt

We have reported that aminopeptidase N/CD13, which metabolizes angiotensin III to angiotensin IV, exhibits greater renal tubular expression in the Dahl salt-resistant (SR/Jr) rat than its salt-sensitive (SS/Jr) counterpart. In this work, aminopeptidase N (Anpep) genes from SS/Jr and SR/Jr strains were compared. The coding regions contained only silent single nucleotide polymorphisms between strains. The 5'...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CCAAT-Enhancer-Binding Protein-alpha
Share to CD13 Antigens

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Disease Models, Animal

Share to Hypertension

Share to Promoter Regions, Genetic

Share to Rats, Inbred Dahl

Share to Rats, Inbred Lew

Source

Identifiers

PMID: 17242304
DOI: 10.1161/01.HYP.0000256303.40359.38

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Functional polymorphism of the Anpep gene increases promoter activity in the Dahl salt-resistant rat.PMID 17242304Read ↗

Locating a blood pressure quantitative trait locus within 117 kb on the rat genome: substitution mapping and renal expression analysis.Semantic proximity Read ↗

Deep transcriptomic profiling of Dahl salt-sensitive rat kidneys with mutant form of Resp18.Semantic proximity Read ↗

Molecular networks in Dahl salt-sensitive hypertension based on transcriptome analysis of a panel of consomic ratsSemantic proximity Read ↗

Polymorphisms in the carboxy-terminus of the epithelial sodium channel in rat models for hypertension.Semantic proximity Read ↗

Characterization and functional analyses of the human G protein-coupled receptor kinase 4 gene promoter.Semantic proximity Read ↗

Epithelial Na+ channel mutants causing Liddle's syndrome retain ability to respond to aldosterone and vasopressin.Semantic proximity Read ↗

Renin-aldosterone response, urinary Na/K ratio and growth in pseudohypoaldosteronism patients with mutations in epithelial sodium channel (ENaC) subunit genes.Semantic proximity Read ↗

Congenic mapping and sequence analysis of the Renin locus.Semantic proximity Read ↗

Chromogranin A polymorphisms are associated with hypertensive renal disease.Semantic proximity Read ↗

Allelic Variants in Arhgef11 via the Rho-Rock Pathway Are Linked to Epithelial-Mesenchymal Transition and Contributes to Kidney Injury in the Dahl Salt-Sensitive Rat.Semantic proximity Read ↗

Transfer of a salt-resistant renin allele raises blood pressure in Dahl salt-sensitive rats.Semantic proximity Read ↗

Pyridoxine 5'-phosphate oxidase is a candidate gene responsible for hypertension in Dahl-S rats.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.