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A Special View of What Was Almost Forgotten: p38δ MAPK

25 Apr 2021

Abstract excerpt

The p38δ mitogen-activated protein kinase is an important signal transduction enzyme. p38δ has recently emerged as a drug target due to its tissue-specific expression patterns and its critical roles in regulation of cellular processes related to cancer and inflammatory diseases, such as cell proliferation, cell migration, apoptosis, and inflammatory responses. However, potent and specific p38δ inhibitors have not...

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PMID: 33923030
DOI: 10.3390/cancers13092077

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