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Article

The B cell antigen receptor controls AP-1 and NFAT activity through Ras-mediated activation of Ral.

Journal of immunology (Baltimore, Md. : 1950) - 1 Feb 2007

de Gorter David J J, Vos Johanna C M, Pals Steven T, Spaargaren Marcel

Abstract excerpt

Signaling by the BCR involves activation of several members of the Ras superfamily of small GTPases, among which is Ras itself. Ras can control the activity of multiple effectors, including Raf, PI3K, and guanine nucleotide exchange factors for the small GTPase Ral. Ras, Raf, and PI3K have been i...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17237388
DOI: 10.4049/jimmunol.178.3.1405

Genes

BCR
ATF2
JUN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17237388-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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