Article
The Ras signal transduction pathway.
Cancer metastasis reviews - 1 Mar 1994
Khosravi-Far R, Der C J
Abstract excerpt
Considerable progress has been made over the past year in elucidating the mechanisms by which extracellular signals are transduced via cell surface receptors to trigger changes in gene expression which determine the growth and differentiated state of a cell. In particular, Ras proteins have been implicated as key intermediates that mediate the signal from upstream tyrosine kinases to a downstream cascade of...
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