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Article

Clinicopathological significance of MMP-2 and TIMP-2 genotypes in gastric cancer.

European journal of cancer (Oxford, England : 1990) - 1 Mar 2007

Wu Chun-Ying, Wu Ming-Shiang, Chen Yi-Ju, Chen Chien-Jen, Chen Hsiao-Ping, Shun Chia-Tung, Chen Gran-Hum, Huang Shih-Pei, Lin Jaw-Town

Abstract excerpt

AIMS: Single nucleotide polymorphisms in matrix metalloproteinase-2 (MMP-2) -1306 C/T and tissue inhibitor of metalloproteinase-2 (TIMP-2) -418 G/C abolish the Sp-1 binding site and down-regulate expression of these genes. We aim to elucidate the role of MMP-2 and TIMP-2 in clinicopathological manifestations of gastric cancer. METHODS: We enrolled 240 gastric cancer patients and 283 controls. DNA was extracted...

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Identifiers

PMID: 17236757
DOI: 10.1016/j.ejca.2006.10.022

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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