Association of Matrix Metallopeptidase-2 Genotypes With Risk of Gastric Cancer in Taiwan.

doi:10.21873/anticanres.15651

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Association of Matrix Metallopeptidase-2 Genotypes With Risk of Gastric Cancer in Taiwan.

Anticancer research - 1 Apr 2022

Fu Chun-Kai, Mong Mei-Chin, Yu Chien-Chih, Yang Mei-Due, Wang Zhi-Hong, Yang Ya-Chen, Chen Jaw-Chyun, Pei Jen-Sheng, Hsia Ning-Yi, Tsai Chia-Wen, Chang Wen-Shin, Bau DA-Tian

Abstract excerpt

BACKGROUND/AIM: Matrix metalloproteinase-2 (MMP-2) plays a critical role in the regulation of the extracellular matrix; however, its genotypes have seldom been examined in gastric cancer (GC). This study aimed to investigate the contribution of MMP-2 promoter -1306 (rs243865) and -735 (rs2285053) genotypes to GC risk in a cohort of Taiwanese individuals. MATERIALS AND METHODS: This study included 121 GC cases and...

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Case-Control Studies
Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Helicobacter Infections

Matrix Metalloproteinase 2

Polymorphism, Single Nucleotide

Risk Factors

Stomach Neoplasms

Taiwan

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PMID: 35346993
DOI: 10.21873/anticanres.15651

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