Article
Tissue inhibitor of metalloproteinase-2 G-418C polymorphism is associated with an increased risk of gastric cancer in a Chinese population.
European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology - 1 Jun 2008
Yang L, Gu H-J, Zhu H-J, Sun Q-M, Cong R-H, Zhou B, Tang N-P, Wang B
Abstract excerpt
AIMS: To examine the effect of the TIMP-2 G-418C polymorphism on gastric cancer risk. METHODS: We conducted a hospital-based, case-control study using polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) method in 412 individuals (206 gastric cancer patients and 206 age, sex matched cancer-free controls). RESULTS: The genotype and allele frequencies were significantly different (P = 0.007...
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