Article
Matrix metalloproteinase-1 (MMP-1) Promoter polymorphisms are well linked with lower stomach tumor formation in eastern Indian population.
PloS one - 1 Jan 2014
Dey Sanjib, Ghosh Nillu, Saha Debjit, Kesh Kousik, Gupta Arnab, Swarnakar Snehasikta
Abstract excerpt
Expression of matrix metalloproteinase-1 (MMP-1), an interstitial collagenase, plays a major role in cellular invasion during development of gastric cancer, a leading cause of death worldwide. A single-nucleotide polymorphism (SNP) -1607 1G/2G site of the MMP-1 gene promoter has been reported to alter transcription level. While the importance's of other SNPs in the MMP-1 promoter have not yet been studied in...
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