Article
Meta-analysis of MMP2 -1306T allele as a protective factor in digestive cancer.
Archives of medical research - 1 Apr 2011
Zhang Le-yao, Ren Ke-wei
Abstract excerpt
BACKGROUND AND AIMS: Matrix metalloproteinase-2 (MMP-2) is an enzyme with proteolytic activity on matrix proteins and abolishes a Sp-1 binding site and consequently decreases its activity. Many studies have been carried out on the association between MMP2 -1306C/T polymorphism and digestive cancer risk, but results were somewhat controversial and underpowered. METHODS: To examine the risk of digestive cancer...
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