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Article

Plasma levels of the proinflammatory chitin-binding glycoprotein YKL-40, variation in the chitinase 3-like 1 gene (CHI3L1), and incident cardiovascular events.

Journal of the American Heart Association - 23 Jun 2014

Ridker Paul M, Chasman Daniel I, Rose Lynda, Loscalzo Joseph, Elias Jack A

Abstract excerpt

BACKGROUND: YKL-40, encoded by the chitinase 3-like 1 (CHI3L1) gene, is a chitinase-like protein involved in innate immune function hypothesized to play a role in the progression of atherosclerosis that may have differential roles in myocardial infarction (MI), as compared to stroke. METHODS AND RESULTS: In a nested case-control study conducted within a prospective cohort of 23 294 initially healthy women of...

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Identifiers

PMID: 24958781
DOI: 10.1161/JAHA.114.000897
PMCID: PMC4309091

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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