Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Effect of deleterious mutations on life span in Drosophila melanogaster.

The journals of gerontology. Series A, Biological sciences and medical sciences - 1 Dec 2006

Gong Yi, Thompson James N, Woodruff R C

Abstract excerpt

Evolutionary theories of aging assume that the accumulation of deleterious mutations will reduce life span. We tested this assumption in Drosophila melanogaster by a newly designed mating scheme, in which mutations accumulate on the Binscy balancer X chromosome in heterozygous females in the absence of selection and recombination. We found that the life span of Binscy/RY(L) males from this cross decreased faster...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aging
Share to Drosophila melanogaster
Share to Longevity

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Models, Statistical

Share to Mortality

Share to Mutation

Source

Identifiers

PMID: 17234817
DOI: 10.1093/gerona/61.12.1246

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Effect of deleterious mutations on life span in Drosophila melanogaster.PMID 17234817Read ↗

Deleterious mutations show increasing negative effects with age in Drosophila melanogaster.Semantic proximity Read ↗

The great evolutionary divide: two genomic systems biologies of aging.Semantic proximity Read ↗

Age-specific effects of novel mutations in Drosophila melanogaster I. Mortality.Semantic proximity Read ↗

The effect of deleterious mutations and age on recombination in Drosophila melanogaster.Semantic proximity Read ↗

On aging and age-specific effects of spontaneous mutations.Semantic proximity Read ↗

Genetic decay of balancer chromosomes in Drosophila melanogaster.Semantic proximity Read ↗

Age-specific effects of novel mutations in Drosophila melanogaster II. Fecundity and male mating ability.Semantic proximity Read ↗

Age-specific changes in epistatic effects on mortality rate in Drosophila melanogaster.Semantic proximity Read ↗

Evidence for a genetic basis of aging in two wild vertebrate populations.Semantic proximity Read ↗

Age-specific effects of deletions: implications for aging theories.Semantic proximity Read ↗

Sex-specific quantitative trait loci affecting longevity in Drosophila melanogaster.Semantic proximity Read ↗

Deleterious genomic mutation rate for viability in Drosophila melanogaster using concomitant sibling controls.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.