Article
Age-specific changes in epistatic effects on mortality rate in Drosophila melanogaster.
The Journal of heredity - 1 Jan 2000
Spencer C C, Promislow D E L
Abstract excerpt
Models for the evolution of senescence assume that genes with age-specific effects act independently of one another. Although recent empirical data show that longevity is influenced in part by interactions between genes, there are currently few data on whether epistasis influences age-specific components of mortality. To gauge if and how interactions affect age-specific traits, we incorporated the Drosophila...
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