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Article

Somatic cell-like features of cloned mouse embryos prepared with cultured myoblast nuclei.

Biology of reproduction - 1 Jul 2003

Gao Shaorong, Chung Young Gie, Williams Jean W, Riley Joan, Moley Kelle, Latham Keith E

Abstract excerpt

Cloning by somatic cell nuclear transfer requires silencing of the donor cell gene expression program and the initiation of the embryonic gene expression program (nuclear reprogramming). Failure to silence the donor cell program could lead to altered embryonic phenotypes. Cloned mouse embryos produced using myoblast nuclei fail to thrive in standard embryo culture media but flourish in somatic cell culture media...

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Source

Identifiers

PMID: 12606377
DOI: 10.1095/biolreprod.102.014522

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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