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Characterization of transcriptional activity during ZGA in mammalian SCNT embryo

30 Jun 2021

Abstract excerpt

Developmental arrest of somatic cell nuclear transfer (SCNT) embryos first occurs at zygotic/embryonic genome activation (ZGA/EGA), which is critical for preimplantation development. However, study on transcriptome of SCNT embryos during ZGA/EGA is limited. In the present study, we performed RNA sequencing (RNA-seq) of the eight-cell SCNT embryos in goat and provide cross-species analysis of transcriptional...

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PMID: 34192747
DOI: 10.1093/biolre/ioab127

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